Publikationen

 

1. Genoud, S., Lappe-Siefke, C., Goebbels, S., Radtke, F.Aguet, M., Scherer, S.S., Suter, U., Nave, K.A.and Mantei, N. 2002.

Notch 1 control of oligodendrocyte differentiation in the spinal cord.

 

J Cell Biol. 158(4):709-718

 

2. Lappe-Siefke, C., Goebbels, S., Gravel, M., Nicksch, E., Lee, J., Braun, P.E., Griffiths, I.R. and Nave, K.A. 2003

Disruption of the CNP gene uncouples oligodendroglial functions in axonal support and myeli­nation.

Nat Genet. 33(3):366-374 

3. Brockschnieder, D., Lappe-Siefke, C., Goebbels, S., Boesl, M.R., Nave, K.A. and Riethmacher, D.2004

Cell Depletion Due to Diphtheria Toxin Fragment A after Cre-Mediated Recombination.

Mol Cell Biol. 24(17):7636–7642

4. Rasband, M.N., Tayler, J., Kaga, Y., Yang, Y., Lappe-Siefke, C., Nave, K.A. and Bansal, R. 2005

 

CNP is required for maintenance of axon-glia interactions at nodes of Ranvier in the CNS.

 

Glia 1(50):86-90

 

5. Saher, G., Brügger, B., Lappe-Siefke, C., Möbius, W., Tozawa, R., Wehr, M.C., Wieland, F., Ishibashi, S. and Nave, K.A. 2005

 

High cholesterol level is essential for myelin membrane growth.

 

Nat Neurosci. 4(8):468-475

 

6. Maas C., Tagnaouti N., Loebrich S., Behrend B., Lappe-Siefke C. and Kneussel M. 2006

Neuronal cotransport of glycine receptor and the scaffold protein gephyrin.

J Cell Biol. 172( 3):441–451

7. Kaga Y., Shoemaker W.J,. Furusho M., Bryant M., Rosenbluth J,. Pfeiffer S.E., Oh L., Rasband M., Lappe-Siefke C., Yu K., Ornitz D.M., Nave K.A. and Bansal R.2006

     

Mice with conditional inactivation of fibroblast growth factor receptor-2 signaling in oligo­dendrocytes have normal myelin but display dramatic hyperactivity when combined with Cnp1 inactivation.

J Neurosci. 26(47):12339-50

8. Kassmann C.M., Lappe-Siefke C., Baes M., Brügger B., Mildner A., Werner H.B., Natt O., Michaelis T., Prinz M., Frahm J. and Nave K.A. 2007

 

Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes.

Nat Genet. 39(8):969-76.

9. Lappe-Siefke C., Maas C. and Kneussel M.2008

Microinjection into cultured hippocampal neurons: a straightforward approach for controlled cellular delivery of nucleic acids, peptides and antibodies.

J Neurosci Methods. 175(1):88-95.

10. Maas C., Belgardt D., Lee H.K., Heisler F.F., Lappe-Siefke C., Magiera M.M., van Dijk J., Hausrat T.J., Janke C., Kneussel M. 2009

 

Synaptic activation modifies microtubules underlying transport of postsynaptic cargo.

PNAS 26 106(21):8731-6.

11. Lappe-Siefke C., Löbrich S., Hevers W., Waidmann O.B., Schweitzer M., Fehr S., Fritschy J.M., Dikic I., Eilers J., Wilson S. and Kneussel M. 2009

 

The ataxia (axJ) mutation causes abnormal GABAA receptor turnover in mice.

PLoS Genet. 5(9):e1000631

12. Goebbels S., Oltrogge J.H., Kemper R., Heilmann I., Bormuth I., Wolfer S., Wichert S.P., Möbius W., Liu X., Lappe-Siefke C., Rossner M.J., Groszer M., Suter U., Frahm J., Boretius S., Nave K.A.2010

 

Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination.

J Neurosci. 30(26):8953-64

13. Schapitz I.U., Behrend B., Pechmann Y., Lappe-Siefke C., Kneussel S.J., Wallace K.E., Stempel A.V., Buck F., Grant S.G., Schweizer M., Schmitz D., Schwarz J.R., Holzbaur E.L., Kneussel M. 2010

Neuroligin 1 is dynamically exchanged at postsynaptic sites.

J Neurosci. 30(38):12733-44.

14. Muhia M., Thies., Labonté D, Ghiretti A.E., Gromova K.V., Xompero F., Lappe-Siefke C., Hermanns-Borgmeyer I., Kuhl D., Schweizer M., Ohana O., Schwarz J.R., Holzbaur E.L.F., Kneussel M. 2016

The kinesin KIF21B regulates microtubule dynamics and is essential for neuronal morphology, synapse function, and learning and memory.

Cell Rep. 15(5):968-977.

 

 

Auszeichnung

 

Im Juni 2004 Verleihung der Otto-Hahn-Medaille für den wissenschaftlichen Nachwuchs durch die Max-Planck-Gesellschaft